Supplies needed1

Iodine solution
Surgical pen
Alcohol to clean area
0.9% nonpreserved sterile saline only
BOTOX® 100 Units
21-gauge, 2-inch extraction needle
30-gauge, ½-inch injection needle

Procedure overview

  1. Perform Minor's Iodine-Starch Test.
  2. Prepare and map treatment area.
  3. Inject BOTOX®.


Perform Minor's Iodine-Starch Test

Patients should shave underarms and abstain from use of over-the-counter deodorants or antiperspirants for 24 hours prior to the test. Patient should be resting comfortably without exercise, hot drinks, etc, for approximately 30 minutes prior to the test. Dry the underarm area and then immediately paint it with iodine solution. Allow the area to dry, then lightly sprinkle the area with starch powder. Gently blow off any excess starch powder. The hyperhidrotic area will develop a deep blue-black color over approximately 10 minutes.

Dry affected axilla. Then immediately paint axilla with iodine solution, making sure to cover excess area around axilla. Allow iodine to dry.

Brush area with starch powder and wait 10 minutes. (A blue-black mark identifies affected area.)


Prepare and map treatment area

Circle affected area with a surgical marker, then clean area inside circle with alcohol.

Use a surgical pen and standard ruler to mark injection points 1.5 to 2 cm apart and staggered.

Count injection points and allocate recommended dosage of BOTOX® solution per injection, based on 50 Units per axilla.


Inject BOTOX®

Inject to a depth of approximately 2 mm and at a 45° angle to skin surface with bevel side up. Be sure not to inject directly on ink mark to avoid a permanent tattoo effect. After injection, clean treated area with alcohol.

Reconstitution and dilution guidelines

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