Rapid and significant symptom improvement with BOTOX® treatment1,2

93% of patients treated with BOTOX® showed an improvement within 48 hours post-injection, and effect reached a peak at 1 or 2 weeks post-treatment (n = 27).1

93%

of Patients

  • In an open-label study, 27 patients with persistent moderate to severe Blepharospasm underwent treatment with BOTOX®1
  • Six sites on each side—the medial and lateral brow, the medial and lateral upper lid, the lateral canthal angle, and the lateral lower lid—were injected with 2.0 Units of BOTOX® using a 27-gauge needle, a total of 12 Units for each eye1,2

Clinical improvements

Mean scores for lid and brow spasm and lid force in patients with Blepharospasm before and after treatment with BOTOX® (n = 27)2,a

Mean Change vs Baseline

In an open-label study, 27 patients with persistent moderate to severe blepharospasm underwent treatment with BOTOX®. Six sites on each side—the medial and lateral brow, the medial and lateral upper lid, the lateral canthal angle, and the lateral lower lid—were injected with 2.0 Units of BOTOX® using a 27-gauge needle, a total of 12 Units for each eye.1

a Eyelid and eyebrow spasm were graded before and after treatment on a 0 to 4 scale: 0 = no spasm; 1 = increased blinking caused by external stimuli; 2 = mild fluttering of the lids; 3 = moderate spasm with mild incapacitation; and 4 = severe spasm resulting in incapacitation. Eyelid force* was also graded on a 0 to 4 scale: 0 = separation of the eyelids with minimal effort to 4 = inability to separate the eyelids with the thumbs.2

*Amount of force exerted against the examiner's fingers by voluntary closure of the lids.

Treating the first BOTOX® patients

Hear what it was like treating the first Blepharospasm patients from Dr. Alan Scott, one of the founders of BOTOX®.

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